Our Research

Omniscient Neurotechnology conducts independent and collaborative research with institutions around the world. Using our Quicktome and Infinitome pipelines, we provide insight into neuropathology through advanced brain mapping and connectomic analyses.


Explore our research

Highlighted Publications

Connectomic disturbances underlying insomnia disorder and predictors of treatment response

August 10, 2022

A high powered prospective study comparing healthy individuals and insomnia patients revealed Connectomic changes in the DMN and associated networks underlying the severity of the disorder.

Prehabilitation and rehabilitation using data-driven, parcel-guided transcranial magnetic stimulation treatment for brain tumor surgery: proof of concept case report

May 14, 2022

A case review demonstrating the utility of o8t software alongside neurorehabilitation to assess functional recovery after glioma removal.

Machine Learning Decomposition of the Anatomy of Neuropsychological Deficit in Alzheimer’s Disease and Mild Cognitive Impairment

May 3, 2022

The Hollow Tree Super (HoTS) method was applied to a patient and healthy control group to define parcels and networks corresponding with diagnosis of MCI and Alzheimers.

Eigenvector PageRank difference as a measure to reveal topological characteristics of the brain connectome for neurosurgery

February 4, 2022

An investigation of two graph theory metrics: Eigenvector and PageRank centrality, and how they together inform unique and neurosurgically meaningful topological characteristics of the brain

Changes in the Brain Connectome Following Repetitive Transcranial Magnetic Stimulation for Stroke Rehabilitation

October 28, 2021

In this case report, we use Infinitome to find optimal targets for rTMS in a patient who had suffered an Ischemic Stroke.

Akinetic mutism reversed by inferior parietal lobule repetitive theta burst stimulation

April 6, 2021

A case study highlighting the benefits of transcranial magnetic stimulation for restoring network functional connectivity in the DMN.

Targeting location relates to treatment response in active but not sham rTMS stimulation

April 1, 2021

A re-opened investigation utilizing o8t atlassing revealed that inaccurate targeting of the dlPFC in veterans reduced treatment response.

Navigated transcranial magnetic stimulation following awake craniotomy for resection of glioma: Description of two cases

December 11, 2020

This dual case study reports on the use of theta burst stimulation (cTBS) for postoperative strategy following brain tumor resection.

Application of structural and functional connectome mismatch for classification and individualized therapy for Alzheimers disease

November 23, 2020

By utilizing the o8t Infinitome processing pipeline, this study revealed connectomic anomalies in the Default Mode Network (DMN) which underpinned the progression of Alzheimer's Disease.

Unexpected hubness: a proof‑of‑concept study of the human connectome using pagerank centrality and implications for intracerebral neurosurgery

November 4, 2020

By utilizing PageRank Centrality, a common algorithm for search engine optimization, we investigated the remapping of neural hubs in individuals suffering from Schizophrenia.

The cortical organization of language: distilling human connectome insights for supratentorial neurosurgery

July 31, 2020

Connectomic approaches have bolstered surgical understanding of the brains major language networks. This manuscript summarizes and reviews these major advancements.

Measuring graphical strength within the connectome: a neuroanatomic, parcellation-based study

October 9, 2019

This study explores the use common graph theory metrics for defining functionally important areas of the cortex. Those we identified heavily overlapped with those known to be surgically eloquent.

Citing our software

Infinitome Neuroscience Platform:

Omniscient Neurotechnology Pty. Ltd. (o8t) (2020). Infinitome [Computer software]. https://infinitome.o8t.com/. Sydney, Australia.

Quicktome Brain Mapping Platform:

Omniscient Neurotechnology Pty. Ltd. (o8t) (2021). Quicktome [Computer software]. https://quicktome.o8t.com/. Sydney, Australia.

Collaboration and future research

We are always interested in engaging with passionate research groups - register your interest to work with our talented data science team below

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