Research & Publications

Omniscient Neurotechnology conducts independent and collaborative research with institutions around the world. We provide insight into neuropathology through advanced brain mapping and connectomic analyses.

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Displaying 1-9 of a total 98 articles. No data to display
Clinical investigation

March 8, 2024
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Quicktome's connectomic analysis on brain malformation surgery exposed 7 unforeseen eloquent regions, highlighting the need for refined surgical strategies and a broader definition of cortical...
Clinical investigation

October 1, 2023
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Neurosurgeons incorporated connectomes into radiosurgical planning, enabling safer dose delivery by protecting crucial brain networks in a patient's AVM treatment.
Clinical investigation

August 7, 2023
Comparison of the pre- and postoperative connectome can be used to objectively evaluate surgical outcomes and assess patient prognosis. To the best of the authors’ knowledge, this is the first case...
Neuropathology

July 6, 2023
Using machine learning, individual brain connectivity analyses reveal unique recovery paths in stroke patients post-treatment.
Clinical investigation

June 1, 2023
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Quicktome revealed functional regions at risk of damage during resection, and it correlated to intraoperative language mapping findings.
Novel analytic techniques

March 22, 2023
Analysed anomaly patterns in anxiety patients, revealing that the default mode network (DMN) is likely the primary network disturbed in anxiety-related disorders.
Novel analytic techniques

March 16, 2023
Found the SCA to be a viable option for pre-surgical planning and general clinical use.
Neuroanatomy

March 13, 2023
We mapped the visual network and found interesting insights on its role in non-visual connections.
Clinical investigation

February 26, 2023
Conducted in collaboration with Shanghai Mental Health Centre, we modelled the anatomical circuits underlying schizophrenia symptoms.
Neuropathology

February 24, 2023
Joint study with Monash University compares functional connectivity patterns in TMS responders vs non-responders for MDD treatment. Machine learning identified potential treatment targets.
Neuropathology

February 15, 2023
Demonstrates how connectomics can be a valuable asset in stroke management when used in predictive modelling of neuro-rehabilitation outcomes.
Neuropathology

January 31, 2023
The correspondence describes a novel scale (the "Sughrue-Ivan" scale) to describe a tumour's location and risk relative to large-scale brain networks.
Novel analytic techniques

January 16, 2023
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Through graphically representing the brain, mathematical graph theory approaches may be able to provide additional information on important inter-individual network properties and functionally...
Neuroanatomy

January 1, 2023
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Meta-analysis of functional connectivity in MDD suggests abnormal interactions between brain networks, particularly increased default mode-central executive pairs and decreased default mode-other...
Neuropathology

September 19, 2022
A retrospective analysis of 100 brain tumor surgery patients using Quicktome. Quicktome showed the extensive involvement of non-traditional networks around regions of pathology that would not...
Clinical investigation

August 10, 2022
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A high powered prospective study comparing healthy individuals and insomnia patients revealed Connectomic changes in the DMN and associated networks underlying the severity of the disorder.
Neuroanatomy

August 5, 2022
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This retrospective investigation of 95 patients operated on between 2012-2017 advocates for the safety of keyhole approaches for removal of giant intracranial tumors.
Clinical investigation

June 14, 2022
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Gerstmann syndrome is a neurological phenomena associated with a variety of motor and cognitive deficits. From a large clinical dataset, we identify brain networks compromised in this syndrome.
Novel analytic techniques

May 14, 2022
A case review demonstrating the utility of o8t software alongside neurorehabilitation to assess functional recovery after glioma removal.
Neuropathology

May 3, 2022
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The Hollow Tree Super (HoTS) method was applied to a patient and healthy control group to define parcels and networks corresponding with diagnosis of MCI and Alzheimers.
Novel analytic techniques

May 3, 2022
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A review of the current applications of Machine Learning and AI in health science data, and how users can avoid common mistakes when handling data.
Neuropathology

April 14, 2022
A report on single-center experience using Quicktome for resection of intra-axial brain tumors
Neuropathology

April 6, 2022
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A meta-analytic approach revealing the cognitive and emotional consequences of damaging brain networks in neurosurgery.
Neuroanatomy

March 25, 2022
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A retrospective assessment of the recent progression in clinical utility of Transcranial Magnetic Stimulation (TMS). The end goal of a patient-specific application is discussed.
Neuropathology

March 8, 2022
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A formal investigation of the prevalence of co-morbid mental health disorders following Glioma diagnosis between 2005-2014
Clinical investigation

February 23, 2022
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A proof-of-concept study demonstrating the capability of o8t software in generating personalized TMS targets for post-craniotomy neurorehabilitation
Novel analytic techniques

February 4, 2022
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An investigation of two graph theory metrics: Eigenvector and PageRank centrality, and how they together inform unique and neurosurgically meaningful topological characteristics of the brain
Neuropathology

January 17, 2022
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A retrospective investigation using Quicktome to demonstrate brain networks compromised by Glioma.
Novel analytic techniques

November 28, 2021
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As the basis for the creation of our patient-specific brain maps, this manuscript unveils the Structural Connectivity Atlas (SCA) methodology
Neuroanatomy

November 28, 2021
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As the basis for the creation of our patient-specific brain maps, this manuscript unveils the Structural Connectivity Atlas (SCA) methodology
Neuropathology

October 28, 2021
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In this case report, we use Infinitome to find optimal targets for rTMS in a patient who had suffered an Ischemic Stroke.
Neuroanatomy

August 26, 2021
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The Precuneus is involved in visuospatial processing and cognition. We reveal the major connections and functions of the precuneus.
Neuropathology

August 16, 2021
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This paper conceptualizes modern neurosurgical approaches from eloquence to centrality. We break down the major breakthroughs in the field which may benefit patient onco-functional balance.
Neuropathology

August 13, 2021
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Using Quicktome, our team re-examined cases of intracerebral surgery and demonstrated a machine-learning approach to investigating the organization of compromised brain networks.
Novel analytic techniques

August 13, 2021
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Using Quicktome, our team re-examined cases of intracerebral surgery and demonstrated a machine-learning approach to investigating the organization of compromised brain networks.
Clinical investigation

June 15, 2021
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A meta-analysis revealing the network constitutents of ideomotor apraxia. We present a connectivity model to explain the determinants of this condition.
Neuroanatomy

June 15, 2021
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A meta-analysis revealing the network constitutents of ideomotor apraxia. We present a connectivity model to explain the determinants of this condition.
Neuroanatomy

April 21, 2021
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The medial occipital lobe, composed of the lingual gyrus and cuneus, is necessary for basic and higher level visual processing. We investigate the connections of the medial occipital lobe.
Novel analytic techniques

April 7, 2021
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This manuscript unveils a novel method for investigating which brain regions are most responsible for greater scores on psychometric tests such as the PANSS for Schizophrenia - Hollow Tree Super.
Clinical investigation

April 6, 2021
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A case study highlighting the benefits of transcranial magnetic stimulation for restoring network functional connectivity in the DMN.
Clinical investigation

April 1, 2021
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A re-opened investigation utilizing o8t atlassing revealed that inaccurate targeting of the dlPFC in veterans reduced treatment response.
Neuroanatomy

March 19, 2021
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The superior parietal lobule (SPL) is involved in somatosensory and visuospatial integration. We reveal the cortical constituents and connections of the SPL.
Neuroanatomy

March 17, 2021
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The Middle Frontal Gyrus (MFG) is involved in attention processing and working memory. We reveal the major connections and functions of the MFG.
Neuroanatomy

March 10, 2021
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The Ventral Premotor Area (VPM) is involved in motor control and execution. We reveal the major connections and functions of the VPM.
Neuropathology

March 5, 2021
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This study provides a retrospective investigation of the utility of Diffusion Tensor Imaging (DTI) for neurosurgical planning of medial frontal gliomas.
Novel analytic techniques

March 5, 2021
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This study provides a retrospective investigation of the utility of Diffusion Tensor Imaging (DTI) for neurosurgical planning of medial frontal gliomas.
Neuroanatomy

February 3, 2021
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The middle temporal gyrus (MTG) is understood to play a role in language related tasks. We investigate the cortical connections and components of the MTG.
Neuroanatomy

January 18, 2021
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The supplementary motor area (SMA) plays a role in the initiation of internally and externally cued movements. This manuscript investigates the cortical connections of the SMA.
Neuroanatomy

January 4, 2021
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The Parahippocampal Gyrus (PHG) is involved in memory encoding and cognition. We reveal the major connections and functions of the PHG.
Neuropathology

December 11, 2020
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This dual case study reports on the use of theta burst stimulation (cTBS) for postoperative strategy following brain tumor resection.
Clinical investigation

November 23, 2020
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By utilizing the o8t Infinitome processing pipeline, this study revealed connectomic anomalies in the Default Mode Network (DMN) which underpinned the progression of Alzheimer's Disease.
Neuroanatomy

November 15, 2020
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The default mode network (DMN) is an important mediator of passive states of mind. We investigate the cortical areas which constitute the DMN.
Neuropathology

November 4, 2020
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By utilizing PageRank Centrality, a common algorithm for search engine optimization, we investigated the remapping of neural hubs in individuals suffering from Schizophrenia.
Novel analytic techniques

November 4, 2020
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By utilizing PageRank Centrality, a common algorithm for search engine optimization, we investigated the remapping of neural hubs in individuals suffering from Schizophrenia.
Neuroanatomy

September 11, 2020
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Many cortical areas co-ordinate human's auditory sense. We present a tractographic model of the brain's primary auditory network
Neuropathology

September 1, 2020
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We present a surgical case study outlining a surgical anomaly: where resection of a tumor in the posterior middle frontal gyrus resulted in pure speech apraxia.
Neuroanatomy

August 10, 2020
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The fusiform gyrus is understood to be involved in the processing of high-order visual information. We characterize its connections by anatomical dissection and fibre tractography.
Neuropathology

July 31, 2020
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Connectomic approaches have bolstered surgical understanding of the brains major language networks. This manuscript summarizes and reviews these major advancements.
Neuroanatomy

July 31, 2020
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Connectomic approaches have bolstered surgical understanding of the brains major language networks. This manuscript summarizes and reviews these major advancements.
Neuroanatomy

May 17, 2020
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This manuscript investigates the cortical connections of the Dorsal Premotor Area (DPM), a critical region for coordinating hand muscle recruitment for motor tasks such as grasping and lifting.
Novel analytic techniques

January 1, 2020
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In this study we explore whether centrality metrics can be utilized to inform the location of surgically eloquent regions. We found PageRank centrality reliably predicted surgically eloquent.
Neuropathology

January 1, 2020
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In this study we explore whether centrality metrics can be utilized to inform the location of surgically eloquent regions. We found PageRank centrality reliably predicted surgically eloquent.
Neuroanatomy

November 21, 2019
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By corroborating tractographic mapping with gross anatomic dissection, we characterize fiber tracts of the Superior Frontal Gyrus (SFG) based on their relationships to known neuroanatomic structures.
Neuroanatomy

November 16, 2019
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The lateral occipital lobe plays a role in object recognition, facial recognition, and motion perception. This manuscript investigates the cortical connections of the lateral occipital lobe.
Neuroanatomy

October 24, 2019
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The ventral attention network (VAN) is an important mediator of stimulus-driven attention. We investigate the cortical areas which constitute the VAN.
Clinical investigation

October 10, 2019
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This manuscript presents a case report, treatment strategy, and subsequent outcomes of a patient suffering a rare bilateral carotid-cavernous fistula (CCF).
Novel analytic techniques

October 9, 2019
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This study explores the use common graph theory metrics for defining functionally important areas of the cortex. Those we identified heavily overlapped with those known to be surgically eloquent.
Neuroanatomy

May 23, 2019
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The dorsal attention network (DAN) is an important mediator of goal‐ directed attentional processing. We investigate the cortical areas which constitute the DAN.
Neuroanatomy

February 28, 2019
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By corroborating tractographic mapping with gross anatomic dissection, we characterize fiber tracts of the Inferior Frontal Gyrus (IFG) based on their relationships to known neuroanatomic structures.
Neuropathology

January 1, 2019
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As part of a larger book on surgical management, this chapter discusses the functional organization of brain networks.
Neuroanatomy

January 1, 2019
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As part of a larger book on surgical management, this chapter discusses the functional organization of brain networks.
Neuropathology

December 6, 2017
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We present a novel hypothesis for the manifestation of Supplementary Motor Area (SMA) syndrome: that damaging the crossed frontal aslant tract subsists this neurosurgical consequence.
Clinical investigation

December 6, 2017
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We present a novel hypothesis for the manifestation of Supplementary Motor Area (SMA) syndrome: that damaging the crossed frontal aslant tract subsists this neurosurgical consequence.
Neuropathology

October 16, 2017
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This manuscript offers expert advice on neurosurgical approaches for glioma removal in the cortex, including how best to preserve eloquent brain regions and their connections.
Neuroanatomy

March 23, 2017
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The orbitofrontal cortex (OFC) is understood to have a role in outcome evaluation and risk assessment. We characterize the connections of the OFC by anatomical dissection and fibre tractography.
Neuroanatomy

December 20, 2016
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By corroborating tractographic mapping with anatomic dissection, we characterize fiber tracts of the Inferior Parietal Lobule (IPL) based on their relationships to known neuroanatomic structures.
Neuropathology

December 20, 2016
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By corroborating tractographic mapping with anatomic dissection, we characterize fiber tracts of the Inferior Parietal Lobule (IPL) based on their relationships to known neuroanatomic structures.
Neuropathology

December 16, 2016
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By assessing the operative results of 43 craniotomy patients, we report on the use and benefit of DTI implementation in surgical workflows.
Novel analytic techniques

December 16, 2016
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By assessing the operative results of 43 craniotomy patients, we report on the use and benefit of DTI implementation in surgical workflows.

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