Our Research

Omniscient Neurotechnology conducts independent and collaborative research with institutions around the world. Using our Quicktome and Infinitome pipelines, we provide insight into neuropathology through advanced brain mapping and connectomic analyses.

 

Explore our research

Highlighted Publications

Connectomic disturbances underlying insomnia disorder and predictors of treatment response

August 10, 2022

A high powered prospective study comparing healthy individuals and insomnia patients revealed Connectomic changes in the DMN and associated networks underlying the severity of the disorder.

A connectivity model of the anatomic substrates underlying Gerstmann syndrome

June 14, 2022

Gerstmann syndrome is a neurological phenomena associated with a variety of motor and cognitive deficits. From a large clinical dataset, we identify brain networks compromised in this syndrome.

Machine Learning Decomposition of the Anatomy of Neuropsychological Deficit in Alzheimer’s Disease and Mild Cognitive Impairment

May 3, 2022

The Hollow Tree Super (HoTS) method was applied to a patient and healthy control group to define parcels and networks corresponding with diagnosis of MCI and Alzheimers.

Transcranial magnetic stimulation for post-operative neurorehabilitation in neuro-oncology: a review of the literature and future directions

March 25, 2022

A retrospective assessment of the recent progression in clinical utility of Transcranial Magnetic Stimulation (TMS). The end goal of a patient-specific application is discussed.

Reducing the cognitive footprint of brain tumor surgery

August 16, 2021

This paper conceptualizes modern neurosurgical approaches from eloquence to centrality. We break down the major breakthroughs in the field which may benefit patient onco-functional balance.

Using Quicktome for Intracerebral Surgery: Early Retrospective Study and Proof of Concept

August 13, 2021

Using Quicktome, our team re-examined cases of intracerebral surgery and demonstrated a machine-learning approach to investigating the organization of compromised brain networks.

A Connectivity Model of the Anatomic Substrates Underlying Ideomotor Apraxia A Meta-Analysis of Functional Neuroimaging Studies

June 15, 2021

A meta-analysis revealing the network constitutents of ideomotor apraxia. We present a connectivity model to explain the determinants of this condition.

Anatomy and white matter connections of the superior parietal lobule

March 19, 2021

The superior parietal lobule (SPL) is involved in somatosensory and visuospatial integration. We reveal the cortical constituents and connections of the SPL.

The Frontal Aslant Tract and Supplementary Motor Area Syndrome: Moving towards a Connectomic Initiation Axis

March 5, 2021

This study provides a retrospective investigation of the utility of Diffusion Tensor Imaging (DTI) for neurosurgical planning of medial frontal gliomas.

Navigated transcranial magnetic stimulation following awake craniotomy for resection of glioma: Description of two cases

December 11, 2020

This dual case study reports on the use of theta burst stimulation (cTBS) for postoperative strategy following brain tumor resection.

Pure Apraxia of Speech After Resection Based in the Posterior Middle Frontal Gyrus

September 1, 2020

We present a surgical case study outlining a surgical anomaly: where resection of a tumor in the posterior middle frontal gyrus resulted in pure speech apraxia.

Beyond eloquence and onto centrality: a new paradigm in planning supratentorial neurosurgery

January 1, 2020

In this study we explore whether centrality metrics can be utilized to inform the location of surgically eloquent regions. We found PageRank centrality reliably predicted surgically eloquent.

Bilateral carotid-cavernous fistulas treated with partial embolization and radiosurgery

October 10, 2019

This manuscript presents a case report, treatment strategy, and subsequent outcomes of a patient suffering a rare bilateral carotid-cavernous fistula (CCF).

Macroconnectomic networks of the human brain

January 1, 2019

As part of a larger book on surgical management, this chapter discusses the functional organization of brain networks.

The crossed frontal aslant tract: a possible pathway involved in the recovery of supplementary motor area syndrome

December 6, 2017

We present a novel hypothesis for the manifestation of Supplementary Motor Area (SMA) syndrome: that damaging the crossed frontal aslant tract subsists this neurosurgical consequence.

Common Disconnections in Glioma Surgery: An Anatomic Description

October 16, 2017

This manuscript offers expert advice on neurosurgical approaches for glioma removal in the cortex, including how best to preserve eloquent brain regions and their connections.

White matter connections of the inferior parietal lobule: A study of surgical anatomy

December 20, 2016

By corroborating tractographic mapping with anatomic dissection, we characterize fiber tracts of the Inferior Parietal Lobule (IPL) based on their relationships to known neuroanatomic structures.

Citing our software

Infinitome Neuroscience Platform:

Omniscient Neurotechnology Pty. Ltd. (o8t) (2020). Infinitome [Computer software]. https://infinitome.o8t.com/. Sydney, Australia.

Quicktome Brain Mapping Platform:

Omniscient Neurotechnology Pty. Ltd. (o8t) (2021). Quicktome [Computer software]. https://quicktome.o8t.com/. Sydney, Australia.

Collaboration and future research

We are always interested in engaging with passionate research groups - register your interest to work with our talented data science team below

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