Neurosurgery

In Neurosurgery, precision is paramount. We conduct research with a neurosurgical focus using connectomics to preserve oncofunctional balance. We aim to offer insight into surgical planning strategy, symptom origin and outcome optimization.

 

Machine Learning Decomposition of the Anatomy of Neuropsychological Deficit in Alzheimer’s Disease and Mild Cognitive Impairment

May 3, 2022

The Hollow Tree Super (HoTS) method was applied to a patient and healthy control group to define parcels and networks corresponding with diagnosis of MCI and Alzheimers.

Association of Low-Grade Glioma Diagnosis and Management Approach with Mental Health Disorders: A MarketScan Analysis 2005-2014

March 8, 2022

A formal investigation of the prevalence of co-morbid mental health disorders following Glioma diagnosis between 2005-2014

Patterns of Traditional and Nontraditional Network Involvement in Insulo-Sylvian Gliomas: An Anatomic Study using the Quicktome Platform

January 17, 2022

A retrospective investigation using Quicktome to demonstrate brain networks compromised by Glioma.

Changes in the Brain Connectome Following Repetitive Transcranial Magnetic Stimulation for Stroke Rehabilitation

October 28, 2021

In this case report, we use Infinitome to find optimal targets for rTMS in a patient who had suffered an Ischemic Stroke.

Reducing the cognitive footprint of brain tumor surgery

August 16, 2021

This paper conceptualizes modern neurosurgical approaches from eloquence to centrality. We break down the major breakthroughs in the field which may benefit patient onco-functional balance.

Using Quicktome for Intracerebral Surgery: Early Retrospective Study and Proof of Concept

August 13, 2021

Using Quicktome, our team re-examined cases of intracerebral surgery and demonstrated a machine-learning approach to investigating the organization of compromised brain networks.

The Frontal Aslant Tract and Supplementary Motor Area Syndrome: Moving towards a Connectomic Initiation Axis

March 5, 2021

This study provides a retrospective investigation of the utility of Diffusion Tensor Imaging (DTI) for neurosurgical planning of medial frontal gliomas.

Navigated transcranial magnetic stimulation following awake craniotomy for resection of glioma: Description of two cases

December 11, 2020

This dual case study reports on the use of theta burst stimulation (cTBS) for postoperative strategy following brain tumor resection.

Unexpected hubness: a proof‑of‑concept study of the human connectome using pagerank centrality and implications for intracerebral neurosurgery

November 4, 2020

By utilizing PageRank Centrality, a common algorithm for search engine optimization, we investigated the remapping of neural hubs in individuals suffering from Schizophrenia.

Pure Apraxia of Speech After Resection Based in the Posterior Middle Frontal Gyrus

September 1, 2020

We present a surgical case study outlining a surgical anomaly: where resection of a tumor in the posterior middle frontal gyrus resulted in pure speech apraxia.

The cortical organization of language: distilling human connectome insights for supratentorial neurosurgery

July 31, 2020

Connectomic approaches have bolstered surgical understanding of the brains major language networks. This manuscript summarizes and reviews these major advancements.

Beyond eloquence and onto centrality: a new paradigm in planning supratentorial neurosurgery

January 1, 2020

In this study we explore whether centrality metrics can be utilized to inform the location of surgically eloquent regions. We found PageRank centrality reliably predicted surgically eloquent.

Macroconnectomic networks of the human brain

January 1, 2019

As part of a larger book on surgical management, this chapter discusses the functional organization of brain networks.

The crossed frontal aslant tract: a possible pathway involved in the recovery of supplementary motor area syndrome

December 6, 2017

We present a novel hypothesis for the manifestation of Supplementary Motor Area (SMA) syndrome: that damaging the crossed frontal aslant tract subsists this neurosurgical consequence.

Common Disconnections in Glioma Surgery: An Anatomic Description

October 16, 2017

This manuscript offers expert advice on neurosurgical approaches for glioma removal in the cortex, including how best to preserve eloquent brain regions and their connections.