March 22, 2023

An agile, data driven approach for target selection in rTMS therapy for anxiety symptoms: Proof of concept and preliminary data for two novel targets

Analysed anomaly patterns in anxiety patients, revealing that the default mode network (DMN) is likely the primary network disturbed in anxiety-related disorders.

February 26, 2023

Symptom-Circuit Mappings of the Schizophrenia Connectome

Conducted in collaboration with Shanghai Mental Health Centre, we modelled the anatomical circuits underlying schizophrenia symptoms.

February 24, 2023

Functional connectivity analysis of the depression connectome provides potential markers and targets for transcranial magnetic stimulation

Joint study with Monash University compares functional connectivity patterns in TMS responders vs non-responders for MDD treatment. Machine learning identified potential treatment targets.

January 1, 2023

Connectivity model of the anatomic substrates and network abnormalities in major depressive disorder: A coordinate meta-analysis of resting-state functional connectivity

Meta-analysis of functional connectivity in MDD suggests abnormal interactions between brain networks, particularly increased default mode-central executive pairs and decreased default mode-other ...

March 8, 2022

Association of Low-Grade Glioma Diagnosis and Management Approach with Mental Health Disorders: A MarketScan Analysis 2005-2014

A formal investigation of the prevalence of co-morbid mental health disorders following Glioma diagnosis between 2005-2014

April 7, 2021

Hollow-tree Super: a directional and scalable approach for feature importance in boosted tree models

This manuscript unveils a novel method for investigating which brain regions are most responsible for greater scores on psychometric tests such as the PANSS for Schizophrenia - Hollow Tree Super.

April 6, 2021

Akinetic mutism reversed by inferior parietal lobule repetitive theta burst stimulation

A case study highlighting the benefits of transcranial magnetic stimulation for restoring network functional connectivity in the DMN.

April 1, 2021

Targeting location relates to treatment response in active but not sham rTMS stimulation

A re-opened investigation utilizing o8t atlassing revealed that inaccurate targeting of the dlPFC in veterans reduced treatment response.

November 23, 2020

Application of structural and functional connectome mismatch for classification and individualized therapy for Alzheimers disease

By utilizing the o8t Infinitome processing pipeline, this study revealed connectomic anomalies in the Default Mode Network (DMN) which underpinned the progression of Alzheimer's Disease.