March 8, 2024

Eloquent noneloquence: redefinition of cortical eloquence based on outcomes of superficial cerebral cavernous malformation resection

Quicktome's connectomic analysis on brain malformation surgery exposed 7 unforeseen eloquent regions, highlighting the need for refined surgical strategies and a broader definition of cortical ...

October 1, 2023

Incorporation of Brain Connectomics for Stereotactic Radiosurgery Treatment Planning

Neurosurgeons incorporated connectomes into radiosurgical planning, enabling safer dose delivery by protecting crucial brain networks in a patient's AVM treatment.

August 7, 2023

Connectomics as a prognostic tool of functional outcome in glioma surgery of the supplementary motor area: illustrative case

Comparison of the pre- and postoperative connectome can be used to objectively evaluate surgical outcomes and assess patient prognosis. To the best of the authors’ knowledge, this is the first case ...

July 6, 2023

Connectomic insight into unique stroke patient recovery after rTMS treatment

Using machine learning, individual brain connectivity analyses reveal unique recovery paths in stroke patients post-treatment.

September 19, 2022

Using machine learning to evaluate large-scale brain networks in patients with brain tumors: Traditional and non-traditional eloquent areas

A retrospective analysis of 100 brain tumor surgery patients using Quicktome. Quicktome showed the extensive involvement of non-traditional networks around regions of pathology that would not ...

August 10, 2022

Connectomic disturbances underlying insomnia disorder and predictors of treatment response

A high powered prospective study comparing healthy individuals and insomnia patients revealed Connectomic changes in the DMN and associated networks underlying the severity of the disorder.

June 14, 2022

A connectivity model of the anatomic substrates underlying Gerstmann syndrome

Gerstmann syndrome is a neurological phenomena associated with a variety of motor and cognitive deficits. From a large clinical dataset, we identify brain networks compromised in this syndrome.

May 3, 2022

Machine Learning Decomposition of the Anatomy of Neuropsychological Deficit in Alzheimer’s Disease and Mild Cognitive Impairment

The Hollow Tree Super (HoTS) method was applied to a patient and healthy control group to define parcels and networks corresponding with diagnosis of MCI and Alzheimers.

April 14, 2022

Early Experience Using Omniscient Neurotechnology Fiber Tracking Software for Resection of Intra-Axial Brain Tumors

A report on single-center experience using Quicktome for resection of intra-axial brain tumors

March 25, 2022

Transcranial magnetic stimulation for post-operative neurorehabilitation in neuro-oncology: a review of the literature and future directions

A retrospective assessment of the recent progression in clinical utility of Transcranial Magnetic Stimulation (TMS). The end goal of a patient-specific application is discussed.

August 16, 2021

Reducing the cognitive footprint of brain tumor surgery

This paper conceptualizes modern neurosurgical approaches from eloquence to centrality. We break down the major breakthroughs in the field which may benefit patient onco-functional balance.

August 13, 2021

Using Quicktome for Intracerebral Surgery: Early Retrospective Study and Proof of Concept

Using Quicktome, our team re-examined cases of intracerebral surgery and demonstrated a machine-learning approach to investigating the organization of compromised brain networks.

June 15, 2021

A Connectivity Model of the Anatomic Substrates Underlying Ideomotor Apraxia A Meta-Analysis of Functional Neuroimaging Studies

A meta-analysis revealing the network constitutents of ideomotor apraxia. We present a connectivity model to explain the determinants of this condition.

March 19, 2021

Anatomy and white matter connections of the superior parietal lobule

The superior parietal lobule (SPL) is involved in somatosensory and visuospatial integration. We reveal the cortical constituents and connections of the SPL.

March 5, 2021

The Frontal Aslant Tract and Supplementary Motor Area Syndrome: Moving towards a Connectomic Initiation Axis

This study provides a retrospective investigation of the utility of Diffusion Tensor Imaging (DTI) for neurosurgical planning of medial frontal gliomas.