June 14, 2022

A connectivity model of the anatomic substrates underlying Gerstmann syndrome

Gerstmann syndrome is a neurological phenomena associated with a variety of motor and cognitive deficits. From a large clinical dataset, we identify brain networks compromised in this syndrome.

April 14, 2022

Early Experience Using Omniscient Neurotechnology Fiber Tracking Software for Resection of Intra-Axial Brain Tumors

A report on single-center experience using Quicktome for resection of intra-axial brain tumors

February 23, 2022

Interventional neurorehabilitation for promoting functional recovery post‑craniotomy: a proof‑of‑concept

A proof-of-concept study demonstrating the capability of o8t software in generating personalized TMS targets for post-craniotomy neurorehabilitation

January 17, 2022

Patterns of Traditional and Nontraditional Network Involvement in Insulo-Sylvian Gliomas: An Anatomic Study using the Quicktome Platform

A retrospective investigation using Quicktome to demonstrate brain networks compromised by Glioma.

November 28, 2021

Connectivity-based parcellation of normal and anatomically distorted human cerebral cortex

As the basis for the creation of our patient-specific brain maps, this manuscript unveils the Structural Connectivity Atlas (SCA) methodology

October 28, 2021

Changes in the Brain Connectome Following Repetitive Transcranial Magnetic Stimulation for Stroke Rehabilitation

In this case report, we use Infinitome to find optimal targets for rTMS in a patient who had suffered an Ischemic Stroke.

June 15, 2021

A Connectivity Model of the Anatomic Substrates Underlying Ideomotor Apraxia A Meta-Analysis of Functional Neuroimaging Studies

A meta-analysis revealing the network constitutents of ideomotor apraxia. We present a connectivity model to explain the determinants of this condition.

April 7, 2021

Hollow-tree Super: a directional and scalable approach for feature importance in boosted tree models

This manuscript unveils a novel method for investigating which brain regions are most responsible for greater scores on psychometric tests such as the PANSS for Schizophrenia - Hollow Tree Super.

April 1, 2021

Targeting location relates to treatment response in active but not sham rTMS stimulation

A re-opened investigation utilizing o8t atlassing revealed that inaccurate targeting of the dlPFC in veterans reduced treatment response.

March 5, 2021

The Frontal Aslant Tract and Supplementary Motor Area Syndrome: Moving towards a Connectomic Initiation Axis

This study provides a retrospective investigation of the utility of Diffusion Tensor Imaging (DTI) for neurosurgical planning of medial frontal gliomas.

November 23, 2020

Application of structural and functional connectome mismatch for classification and individualized therapy for Alzheimers disease

By utilizing the o8t Infinitome processing pipeline, this study revealed connectomic anomalies in the Default Mode Network (DMN) which underpinned the progression of Alzheimer's Disease.

November 4, 2020

Unexpected hubness: a proof‑of‑concept study of the human connectome using pagerank centrality and implications for intracerebral neurosurgery

By utilizing PageRank Centrality, a common algorithm for search engine optimization, we investigated the remapping of neural hubs in individuals suffering from Schizophrenia.

July 31, 2020

The cortical organization of language: distilling human connectome insights for supratentorial neurosurgery

Connectomic approaches have bolstered surgical understanding of the brains major language networks. This manuscript summarizes and reviews these major advancements.

January 1, 2020

Beyond eloquence and onto centrality: a new paradigm in planning supratentorial neurosurgery

In this study we explore whether centrality metrics can be utilized to inform the location of surgically eloquent regions. We found PageRank centrality reliably predicted surgically eloquent.

October 9, 2019

Measuring graphical strength within the connectome: a neuroanatomic, parcellation-based study

This study explores the use common graph theory metrics for defining functionally important areas of the cortex. Those we identified heavily overlapped with those known to be surgically eloquent.