January 25, 2025
Enhancing brain tumor surgery precision with multimodal connectome imaging: Structural and functional connectivity in language-dominant areas
Multimodal connectome imaging may enhance brain tumor surgery by providing structural and functional connectivity insights, aiding in precise resection while preserving language function. This case ...
March 8, 2024
Eloquent noneloquence: redefinition of cortical eloquence based on outcomes of superficial cerebral cavernous malformation resection
Quicktome's connectomic analysis on brain malformation surgery exposed 7 unforeseen eloquent regions, highlighting the need for refined surgical strategies and a broader definition of cortical ...
March 22, 2023
An agile, data driven approach for target selection in rTMS therapy for anxiety symptoms: Proof of concept and preliminary data for two novel targets
Analysed anomaly patterns in anxiety patients, revealing that the default mode network (DMN) is likely the primary network disturbed in anxiety-related disorders.
March 13, 2023
Topology of the lateral visual system: The fundus of the superior temporal sulcus and parietal area H connect non-visual cerebrum to the lateral occipital lobe
We mapped the visual network and found interesting insights on its role in non-visual connections.
February 26, 2023
Symptom-Circuit Mappings of the Schizophrenia Connectome
Conducted in collaboration with Shanghai Mental Health Centre, we modelled the anatomical circuits underlying schizophrenia symptoms.
February 15, 2023
Connectomics underlying motor functional outcomes in the acute period following stroke
Demonstrates how connectomics can be a valuable asset in stroke management when used in predictive modelling of neuro-rehabilitation outcomes.
October 28, 2021
Changes in the Brain Connectome Following Repetitive Transcranial Magnetic Stimulation for Stroke Rehabilitation
In this case report, we use Infinitome to find optimal targets for rTMS in a patient who had suffered an Ischemic Stroke.
April 1, 2021
Targeting location relates to treatment response in active but not sham rTMS stimulation
A re-opened investigation utilizing o8t atlassing revealed that inaccurate targeting of the dlPFC in veterans reduced treatment response.
November 23, 2020
Application of structural and functional connectome mismatch for classification and individualized therapy for Alzheimers disease
By utilizing the o8t Infinitome processing pipeline, this study revealed connectomic anomalies in the Default Mode Network (DMN) which underpinned the progression of Alzheimer's Disease.
November 4, 2020
Unexpected hubness: a proof‑of‑concept study of the human connectome using pagerank centrality and implications for intracerebral neurosurgery
By utilizing PageRank Centrality, a common algorithm for search engine optimization, we investigated the remapping of neural hubs in individuals suffering from Schizophrenia.
July 31, 2020
The cortical organization of language: distilling human connectome insights for supratentorial neurosurgery
Connectomic approaches have bolstered surgical understanding of the brains major language networks. This manuscript summarizes and reviews these major advancements.
October 9, 2019
Measuring graphical strength within the connectome: a neuroanatomic, parcellation-based study
This study explores the use common graph theory metrics for defining functionally important areas of the cortex. Those we identified heavily overlapped with those known to be surgically eloquent.
