January 25, 2025
Enhancing brain tumor surgery precision with multimodal connectome imaging: Structural and functional connectivity in language-dominant areas
Multimodal connectome imaging may enhance brain tumor surgery by providing structural and functional connectivity insights, aiding in precise resection while preserving language function. This case ...
January 4, 2025
Connectome imaging to facilitate preservation of the frontal aslant tract
Connectome imaging was used to assist in preserving the frontal aslant tract (FAT) during tumor resection. This case study highlights the role of preoperative tractography in reducing the risk of ...
March 8, 2024
Eloquent noneloquence: redefinition of cortical eloquence based on outcomes of superficial cerebral cavernous malformation resection
Quicktome's connectomic analysis on brain malformation surgery exposed 7 unforeseen eloquent regions, highlighting the need for refined surgical strategies and a broader definition of cortical ...
January 6, 2024
Connectome-Based Neurosurgery in Primary Intra-Axial Neoplasms
Despite advances in surgical treatments for brain tumors improving survival, connectomics enables a nuanced focus on preserving patients' neurocognitive functions and life reintegration.
July 6, 2023
Connectomic insight into unique stroke patient recovery after rTMS treatment
Using machine learning, individual brain connectivity analyses reveal unique recovery paths in stroke patients post-treatment.
June 1, 2023
Case Study: Intraoperative awake language mapping correlates to preoperative connectomics imaging: An instructive case
Quicktome revealed functional regions at risk of damage during resection, and it correlated to intraoperative language mapping findings.
March 22, 2023
An agile, data driven approach for target selection in rTMS therapy for anxiety symptoms: Proof of concept and preliminary data for two novel targets
Analysed anomaly patterns in anxiety patients, revealing that the default mode network (DMN) is likely the primary network disturbed in anxiety-related disorders.
March 16, 2023
Real World Demonstration of Hand Motor Mapping using the Structural Connectivity Atlas
Found the SCA to be a viable option for pre-surgical planning and general clinical use.
March 13, 2023
Topology of the lateral visual system: The fundus of the superior temporal sulcus and parietal area H connect non-visual cerebrum to the lateral occipital lobe
We mapped the visual network and found interesting insights on its role in non-visual connections.
February 26, 2023
Symptom-Circuit Mappings of the Schizophrenia Connectome
Conducted in collaboration with Shanghai Mental Health Centre, we modelled the anatomical circuits underlying schizophrenia symptoms.
February 15, 2023
Connectomics underlying motor functional outcomes in the acute period following stroke
Demonstrates how connectomics can be a valuable asset in stroke management when used in predictive modelling of neuro-rehabilitation outcomes.
January 31, 2023
Letter to the editor: Standardizing connectome-based brain tumor surgery through a network-based surgical nomenclature
The correspondence describes a novel scale (the "Sughrue-Ivan" scale) to describe a tumour's location and risk relative to large-scale brain networks.
January 16, 2023
Review: Graph Theory Measures and Their Application to Neurosurgical Eloquence
Through graphically representing the brain, mathematical graph theory approaches may be able to provide additional information on important inter-individual network properties and functionally ...
January 1, 2023
Connectivity model of the anatomic substrates and network abnormalities in major depressive disorder: A coordinate meta-analysis of resting-state functional connectivity
Meta-analysis of functional connectivity in MDD suggests abnormal interactions between brain networks, particularly increased default mode-central executive pairs and decreased default mode-other ...
September 19, 2022
Using machine learning to evaluate large-scale brain networks in patients with brain tumors: Traditional and non-traditional eloquent areas
A retrospective analysis of 100 brain tumor surgery patients using Quicktome. Quicktome showed the extensive involvement of non-traditional networks around regions of pathology that would not ...
