Our Research

Omniscient Neurotechnology conducts independent and collaborative research with institutions around the world. Using our Quicktome and Infinitome pipelines, we provide insight into neuropathology through advanced brain mapping and connectomic analyses.

 

Explore our research

Highlighted Publications

A connectivity model of the anatomic substrates underlying Gerstmann syndrome

June 14, 2022

Gerstmann syndrome is a neurological phenomena associated with a variety of motor and cognitive deficits. From a large clinical dataset, we identify brain networks compromised in this syndrome.

Interventional neurorehabilitation for promoting functional recovery post‑craniotomy: a proof‑of‑concept

February 23, 2022

A proof-of-concept study demonstrating the capability of o8t software in generating personalized TMS targets for post-craniotomy neurorehabilitation

Patterns of Traditional and Nontraditional Network Involvement in Insulo-Sylvian Gliomas: An Anatomic Study using the Quicktome Platform

January 17, 2022

A retrospective investigation using Quicktome to demonstrate brain networks compromised by Glioma.

Connectivity-based parcellation of normal and anatomically distorted human cerebral cortex

November 28, 2021

As the basis for the creation of our patient-specific brain maps, this manuscript unveils the Structural Connectivity Atlas (SCA) methodology

Changes in the Brain Connectome Following Repetitive Transcranial Magnetic Stimulation for Stroke Rehabilitation

October 28, 2021

In this case report, we use Infinitome to find optimal targets for rTMS in a patient who had suffered an Ischemic Stroke.

A Connectivity Model of the Anatomic Substrates Underlying Ideomotor Apraxia A Meta-Analysis of Functional Neuroimaging Studies

June 15, 2021

A meta-analysis revealing the network constitutents of ideomotor apraxia. We present a connectivity model to explain the determinants of this condition.

Hollow-tree Super: a directional and scalable approach for feature importance in boosted tree models

April 7, 2021

This manuscript unveils a novel method for investigating which brain regions are most responsible for greater scores on psychometric tests such as the PANSS for Schizophrenia - Hollow Tree Super.

Targeting location relates to treatment response in active but not sham rTMS stimulation

April 1, 2021

A re-opened investigation utilizing o8t atlassing revealed that inaccurate targeting of the dlPFC in veterans reduced treatment response.

The Frontal Aslant Tract and Supplementary Motor Area Syndrome: Moving towards a Connectomic Initiation Axis

March 5, 2021

This study provides a retrospective investigation of the utility of Diffusion Tensor Imaging (DTI) for neurosurgical planning of medial frontal gliomas.

Application of structural and functional connectome mismatch for classification and individualized therapy for Alzheimers disease

November 23, 2020

By utilizing the o8t Infinitome processing pipeline, this study revealed connectomic anomalies in the Default Mode Network (DMN) which underpinned the progression of Alzheimer's Disease.

Unexpected hubness: a proof‑of‑concept study of the human connectome using pagerank centrality and implications for intracerebral neurosurgery

November 4, 2020

By utilizing PageRank Centrality, a common algorithm for search engine optimization, we investigated the remapping of neural hubs in individuals suffering from Schizophrenia.

The cortical organization of language: distilling human connectome insights for supratentorial neurosurgery

July 31, 2020

Connectomic approaches have bolstered surgical understanding of the brains major language networks. This manuscript summarizes and reviews these major advancements.

Beyond eloquence and onto centrality: a new paradigm in planning supratentorial neurosurgery

January 1, 2020

In this study we explore whether centrality metrics can be utilized to inform the location of surgically eloquent regions. We found PageRank centrality reliably predicted surgically eloquent.

Measuring graphical strength within the connectome: a neuroanatomic, parcellation-based study

October 9, 2019

This study explores the use common graph theory metrics for defining functionally important areas of the cortex. Those we identified heavily overlapped with those known to be surgically eloquent.

Citing our software

Infinitome Neuroscience Platform:

Omniscient Neurotechnology Pty. Ltd. (o8t) (2020). Infinitome [Computer software]. https://infinitome.o8t.com/. Sydney, Australia.

Quicktome Brain Mapping Platform:

Omniscient Neurotechnology Pty. Ltd. (o8t) (2021). Quicktome [Computer software]. https://quicktome.o8t.com/. Sydney, Australia.

Collaboration and future research

We are always interested in engaging with passionate research groups - register your interest to work with our talented data science team below

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