Our Research
Omniscient Neurotechnology conducts independent and collaborative research with institutions around the world. Using our Quicktome and Infinitome pipelines, we provide insight into neuropathology through advanced brain mapping and connectomic analyses.
Explore our research
Highlighted Publications
A connectivity model of the anatomic substrates underlying Gerstmann syndrome
June 14, 2022
Gerstmann syndrome is a neurological phenomena associated with a variety of motor and cognitive deficits. From a large clinical dataset, we identify brain networks compromised in this syndrome.
Interventional neurorehabilitation for promoting functional recovery post‑craniotomy: a proof‑of‑concept
February 23, 2022
A proof-of-concept study demonstrating the capability of o8t software in generating personalized TMS targets for post-craniotomy neurorehabilitation
Patterns of Traditional and Nontraditional Network Involvement in Insulo-Sylvian Gliomas: An Anatomic Study using the Quicktome Platform
January 17, 2022
A retrospective investigation using Quicktome to demonstrate brain networks compromised by Glioma.
Connectivity-based parcellation of normal and anatomically distorted human cerebral cortex
November 28, 2021
As the basis for the creation of our patient-specific brain maps, this manuscript unveils the Structural Connectivity Atlas (SCA) methodology
Changes in the Brain Connectome Following Repetitive Transcranial Magnetic Stimulation for Stroke Rehabilitation
October 28, 2021
In this case report, we use Infinitome to find optimal targets for rTMS in a patient who had suffered an Ischemic Stroke.
A Connectivity Model of the Anatomic Substrates Underlying Ideomotor Apraxia A Meta-Analysis of Functional Neuroimaging Studies
June 15, 2021
A meta-analysis revealing the network constitutents of ideomotor apraxia. We present a connectivity model to explain the determinants of this condition.
Hollow-tree Super: a directional and scalable approach for feature importance in boosted tree models
April 7, 2021
This manuscript unveils a novel method for investigating which brain regions are most responsible for greater scores on psychometric tests such as the PANSS for Schizophrenia - Hollow Tree Super.
Targeting location relates to treatment response in active but not sham rTMS stimulation
April 1, 2021
A re-opened investigation utilizing o8t atlassing revealed that inaccurate targeting of the dlPFC in veterans reduced treatment response.
The Frontal Aslant Tract and Supplementary Motor Area Syndrome: Moving towards a Connectomic Initiation Axis
March 5, 2021
This study provides a retrospective investigation of the utility of Diffusion Tensor Imaging (DTI) for neurosurgical planning of medial frontal gliomas.
Application of structural and functional connectome mismatch for classification and individualized therapy for Alzheimers disease
November 23, 2020
By utilizing the o8t Infinitome processing pipeline, this study revealed connectomic anomalies in the Default Mode Network (DMN) which underpinned the progression of Alzheimer's Disease.
Unexpected hubness: a proof‑of‑concept study of the human connectome using pagerank centrality and implications for intracerebral neurosurgery
November 4, 2020
By utilizing PageRank Centrality, a common algorithm for search engine optimization, we investigated the remapping of neural hubs in individuals suffering from Schizophrenia.
The cortical organization of language: distilling human connectome insights for supratentorial neurosurgery
July 31, 2020
Connectomic approaches have bolstered surgical understanding of the brains major language networks. This manuscript summarizes and reviews these major advancements.
Beyond eloquence and onto centrality: a new paradigm in planning supratentorial neurosurgery
January 1, 2020
In this study we explore whether centrality metrics can be utilized to inform the location of surgically eloquent regions. We found PageRank centrality reliably predicted surgically eloquent.
Measuring graphical strength within the connectome: a neuroanatomic, parcellation-based study
October 9, 2019
This study explores the use common graph theory metrics for defining functionally important areas of the cortex. Those we identified heavily overlapped with those known to be surgically eloquent.
Citing our software
Infinitome Neuroscience Platform:
Omniscient Neurotechnology Pty. Ltd. (o8t) (2020). Infinitome [Computer software]. https://infinitome.o8t.com/. Sydney, Australia.
Quicktome Brain Mapping Platform:
Omniscient Neurotechnology Pty. Ltd. (o8t) (2021). Quicktome [Computer software]. https://quicktome.o8t.com/. Sydney, Australia.